Autologous wound care

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ActiGraft^®Powered by the patient's own blood

ActiGraft® is a point-of-care wound management system. A small sample of the patient's own peripheral blood is mixed with the coagulation powder in the kit. This forms a whole blood clot, which is applied to the wound surface as a protective covering.

It comes in two versions with the same kit and the same 28 cm² clot: ActiGraft Plus for office and mobile providers, and ActiGraft Pro for hospital outpatient departments.

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The ActiGraft Difference

Advanced Technology. Remarkably Simple.

Innovation that fits clinical practice, not the other way around.

The patient's own blood

Made from the patient's peripheral whole blood. No bovine, porcine or placental materials.

No centrifuge

The blood is mixed with the powder in the kit. Nothing to spin and no extra equipment.

About 5 minutes

The clot forms at point of care in about 5 minutes. Blood can be drawn and stored up to 24 hours before the procedure.

Up to 56 cm²

Each kit makes one 28 cm² clot, which can be applied to wounds up to 56 cm².

Published Clinical Research

Meaningful Science. Measurable Results.

A multicenter, randomized controlled trial of 119 patients with hard-to-heal diabetic foot ulcers, at 16 sites in the US, South Africa and Turkey. It compared the autologous whole blood clot plus standard of care with standard of care alone.

Snyder R, Nouvong A, Ulloa J, et al. “Efficacy and safety of autologous whole blood clot in diabetic foot ulcers: a randomised controlled trial.” Journal of Wound Care, 2024;33(9):688–700. Read the published study(opens in a new tab)

Read the peer-reviewed articles (PDF)(opens in a new tab)

These results describe the patients in this trial. They are not a promise of results for any one patient. Always follow the maker's instructions for use.

Results

Complete wound closure at 12 weeks

Whole blood clot + standard of care
Standard of care alone

Intention-to-treat

Whole blood clot + standard of care: 41%
Standard of care alone: 15%

Per-protocol

Whole blood clot + standard of care: 51%
Standard of care alone: 18%

The Right Fit for Your Setting

Two Solutions. One Innovative Technology.

Explore the ActiGraft option aligned with your care environment, with guidance from the DRI team.

Office and mobile

ActiGraft Plus

For office-based and mobile wound care, including independent physician practices and mobile providers.

Order code RD2201 · 5 kits per box

Ask for a quote

An open ActiGraft kit: step-by-step pictures inside the lid, and the single-use parts in a tray — One kit holds all the single-use parts needed to prepare one clot.

Hospital outpatient

ActiGraft Pro

For hospital outpatient departments.

Order code RD2301 · 5 kits per box

Ask for a quote

Information for Clinical Teams

Clinical & Product Resources

Practical information and source documents for your team's evaluation.

Intended use and safety

FDA-cleared for the topical management of exuding cutaneous wounds under the supervision of a healthcare professional
Diabetic foot ulcers
Venous leg ulcers
Pressure ulcers and injuries
Surgically and mechanically debrided wounds

From the maker's information. Always follow the maker's instructions for use, its warnings, and your facility's protocols.

Storage and handling

Store at 41°F to 86°F (5°C to 30°C).
The parts in the kit are single use.

Coverage and reimbursement

The maker lists HCPCS code G0465 for diabetic chronic wounds, under Medicare's National Coverage Determination 270.3. Coverage and payment depend on each payer's policy, medical necessity and clinical documentation.

Reimbursement is not guaranteed. Ask us for the maker's reimbursement resources.

DocumentsActiGraft Plus brochure · ActiGraft Pro brochure · Instructions for use. Sent by email on request.Ask for a document

ActiGraft® is a product of RedDress. All trademarks belong to their owners.

The DRI Experience

The Technology Is Innovative. Our Commitment Is Personal.

Your partnership with DRI doesn't end with product selection.

We take the time to understand each provider's clinical and operational priorities, from hospitals and wound care centers to independent physician practices, mobile clinics, home health organizations, skilled nursing facilities and long-term care providers.

Expect thoughtful guidance, responsive communication, and personalized attention every step of the way.

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Live Assistance

Real people. Real answers. When you need us.

FAQ

Questions About ActiGraft

What is the difference between ActiGraft Plus and ActiGraft Pro?

They hold the same kit and make the same 28 cm² clot. The difference is the packaging and the care setting: ActiGraft Plus is for office and mobile providers, and ActiGraft Pro is for hospital outpatient departments.

Can it be prepared for patients on blood thinners?

The maker states that ActiGraft can be prepared from a patient's peripheral whole blood even when the patient is on blood thinners. The maker's instructions for use give the full details.

Is there a billing code?

Is there published research?

Yes. The maker cites a randomized controlled trial: Snyder R, Nouvong A, Ulloa J, et al. “Efficacy and safety of autologous whole blood clot in diabetic foot ulcers: a randomised controlled trial.” Journal of Wound Care, 2024;33(9):688–700. Its results are shown on this page, and we can send the maker's brochure.

Can I get the maker's documents?

Yes. We can send the maker's product information and instructions for use by email. Use “Ask for a document” on this page, or just ask.

Let’s Build Something Exceptional

Discover What ActiGraft Could Bring to Your Practice

Whether you serve patients in a hospital, independent practice, mobile clinic or home-based setting, DRI Wound Care is ready to explore the right solution with you.

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Innovative by Vision. Personal by Nature. Exceptional by Commitment.

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